Natural Born Killers es la banda sonora de la película del mismo nombre, producido por Trent Reznor de Nine Inch Nails. Reznor produjó la banda sonora con un portátil de Pro Tools en su habitación de hotel mientras estaba de gira.En su acercamiento a la compilación de la banda sonora, Reznor dijo a MTV:
Le sugerí a Oliver [Stone] tratar de convertir la banda sonora en un collage de sonido, hacer cambios, añadir diálogo, y hacer algo interesante, más que un montón de música lanzada previamente.
Algunas canciones fueron escritas especialmente para la película, como por ejemplo "Burn"de Nine Inch Nails, y "What Would You Do", por Tha Dogg Pound.
- Leonard Cohen — "Waiting for the Miracle"
- L7 — "Shitlist"
- Dan Zanes — "Moon over Greene County"
- Patti Smith — "Rock N Roll Nigger"
- Cowboy Junkies — "Sweet Jane"
- Bob Dylan — "You Belong to Me"
- Duane Eddy — "The Trembler"
- Nine Inch Nails — "Burn"
- "Route 666"featuring Robert Downey Jr., and Brian Berdan — "BB Tone"
- "Totally Hot"contains an edit of Remmy Ongala And Orchestre Super Matimila — "Kipenda Roho"
- Patsy Cline — "Back in Baby's Arms"
- Peter Gabriel And Nusrat Fateh Ali Khan — "Taboo"
- "Sex Is Violent"contains excerpts of Jane's Addiction — "Ted, Just Admit It..." and Diamanda Galás — "I Put a Spell on You"
- A.O.S. — "History (Repeats Itself)"
- Nine Inch Nails — "Something I Can Never Have"
- Russel Means — "I Will Take You Home"
- The Hollywood Persuaders — "Drums a Go-Go"
- "Hungry Ants"contains excerpts of Barry Adamson — "Checkpoint Charlie" and "Violation of Expectation"
- Dr. Dre — "The Day the Niggaz Took Over"
- Juliette Lewis — "Born Bad"
- Sergio Cervetti — "Fall of the Rebel Angels"
- Lard — "Forkboy"
- "Batonga In Batongaville"contains excerpts of The Budapest Philharmonic Orchestra — "A Night on Bare Mountain"
- Nine Inch Nails — "A Warm Place"
- "Allah, Mohammed, Char, Yaar"contains excerpts of Nusrat Fateh Ali Khan & Party — "Allah, Mohammed, Char, Yaar" and Diamanda Galás — "Judgement Day"
- Leonard Cohen — "The Future"
- Tha Dogg Pound — "What Would U Do?"
